BAUNEZ Christelle

Name : BAUNEZ
Surname : Christelle
Phone : 04 91 32 40 62
Fonction : chef d'équipe
Grade : DR1
Office : 0.01

Biography

RECENT PUBLICATION-MEDIA COMMUNICATION: The media communication from the CNRS: https://www.cnrs.fr/en/brain-signat...https://www.cnrs.fr/en/brain-signat...

The paper: Proc Natl Acad Sci U S A 2021 Apr 6;118(14):e2024121118. doi: 10.1073/pnas.2024121118. Subthalamic low-frequency oscillations predict vulnerability to cocaine addiction Mickael Degoulet, Alix Tiran-Cappello, Etienne Combrisson, Christelle Baunez*, Yann Pelloux*

Main topic of research

The involvement of the subthalamic nucleus in reward-related processes and their dysregulation including the loss of inhibitory control (impulsivity and compulsivity) and addiction in the rat mostly, with collaborations for projects in monkeys and human subjects.

URGENT HIRING ANNOUNCEMENTS!!!: Urgent post-doc position available as soon as possible. Profile required: In vivo freely-moving electrophysiology in rats. One year contract (can be extended to 2 years on another project, to be discussed).

Post-doc position available for 2 years. Topic: Subthalamic nucleus network in fMRI, social regulation of decision making in alcohol users Profile: Experience with fMRI and data analysis. Project in collaboration with D. Grandjean (Univ. Geneva) and T. Chaminade (INT, team Banco)

send me your CV, letter of motivation and 2 references

Invited international conferences (last 5 years):

2015

- “DBS and optogenetic manipulation of STN on motivational processes and addiction” C. Baunez OptoDBS, Geneva 7-9 mai 2015

- “The subthalamic nucleus: a critical node where emotion can modulate motivation ” C. Baunez INT international workshop series on “Social motivation and reward system“, Marseille 17-18 september 2015

2016

- “The subthalamic nucleus (STN) in the control of inhibition: relevance to decision making, loss chasing and addiction“ C . Baunez Symposium « Mechanistic relevance of deep brain stimulation targets for obsessive compulsive disorder » (Org. V. Voon & C. Baunez) EWCBR 2016, Villars sur Ollon, Switzerland, 5-12 march 2016

- “Deep Brain Stimulation of the subthalamic nucleus as a possible treatment for addiction” C. Baunez 5th Basic and Clinical Neuroscience Congress, Teheran, Iran, 7-9 december 2016

2017

- “The affective and social rat subthalamic nucleus” C. Baunez in symposium “The role of the STN in emotional processing: new insights from animal and human research” (org. D. Grandjean) EWCBR 2017, Les Arcs 1800, 4-10 march 2017

- “Turn conservative after subthalamic nucleus inactivation“ C. Baunez International Symposium on Biology of Decision Making, Bordeaux, May 15-17 2017

- “The Subthalamic Nucleus at the Nexus of Decision-Making Processes » C. Baunez in symposium « Decision Making and the Subthalamic Nucleus across species: Subcircuitry and Relevance to Neuropsychiatry » (org. V. Voon) Society of Biological Psychiatry Meeting, San Diego, May 18-20 2017

- “Surgical strategy for addiction based on rats and monkeys studies using deep brain stimulation applied at the level of the subthalamic nucleus “ C. Baunez Mediterranean Neuroscience Society Meeting, Malta, June 12-15 2017

- “DBS and optogenetic manipulations of the STN on addiction criteria in the rat” C Baunez OptoDBS2017, Geneva, Switzerland, June 22-24 2017

- “Animal models for psychiatric disorders » C. Baunez in symposium "Surgery for psychiatric disorders" (org. Bart Nuttin, Keith Matthews and Marwan Hariz) World Society for Stereotactic and Functional Neurosurgery, Berlin, Germany, June 26-29 2017

- “STN proximal social factors “ C. Baunez 17th EBPS biennial meeting Heraklion, Greece, 31 august-3 september 2017

2018

- Symposium “The Neglected Nuclei of Addiction: Putting Understudied Brain Regions in the Limelight » , Winter Conference on Brain Research, Whistler (Canada) January 14 - 19, 2018

- Symposium “Beyond emotions: basal ganglia, amygdala and cortex: from pharmacological to electrical neuromodulation” EWCBR Villars sur Ollon

- “Contribution of STN Oscillations to Compulsive Drug Seeking: Positioning the STN as a Target for Surgical Treatment of Drug Addiction » C. Baunez, Gordon conference on the Basal Ganglia, Chair:. M. Bevan, March 11-16, 2018

53- plenary lecture “Translational approach for better risk reduction and potential treatment for addiction“ C. Baunez, Science of Translation: Optimizing Animal Models for Neuropsychiatry, Köln, Germany, May 24-25, 2018

54- “Are Antifragile Exposures Natural? » Pintus P and Baunez C, BEAM - ABEE Workshop, Experimental and Behavioral Analyses in Macroeconomics and Finance, Amsterdam, The Netherlands 24-25 august 2018

55- “Basics of addiction” C. Baunez, XXIII congress of the European Society for Stereotactic and Functional Neurosurgery (ESSFN) Edinburgh, United Kingdom, 26-29/09/2018

56- “DBS for addiction in pre-clinical studies” C. Baunez, 2018 Eastern DBS Think Tank planning meeting, Shanghai, China, 10-11 october 2018

2019

57-"Modulation of cocaine intake by ultrasonic vocalizations in rats" C. Baunez in symposium Vocal emotions: neural bases and behavioural consequences organized by D. Grandjean, 39th EWCBR, Les Arcs, France, 17-22 mars 2019

58- "STN oscillatory activity as a predictor of compulsive cocaine seeking" C. Baunez symposium " Circuits and systems of motivation and addiction" organized by C. Baunez, 39th EWCBR, Les Arcs, France, 17-22 mars 2019

59- "Subthalamic nucleus and maladaptive control of inhibition and its related pathologies" C. Baunez, IBAGS, Biarritz, France, 28th April-May 2nd 2019

60- "Mechanisms underlying impulsive behaviors and addictions in Parkinson’s disease-translationaI studies in animal models and patients" C. Baunez, 5th World Parkinson Congress, Kyoto, Japan, June 4-7 2019

61-" Translational evidence of the subthalamic nucleus involvement in decision-making processes, impulsivity and compulsivity" C. Baunez, IBNS, Cairns, Australia, June 23-27 2019

62- " The subthalamic nucleus: an unexpected critical node in the reward circuit " C.Baunez 6th Bordeaux Neurocampus Conference : Normal and parhological reward processing: from synapse to behavior. Bordeaux, France, October 2nd-4th 2019

63- “Subthalamic nucleus DBS and addiction” C. Baunez, The Neurosurgical Treatments for Psychiatric Disorders Summit 2019, Shanghai, China, november 8-10th 2019

2020

64- “Role of the subthalamic nucleus in Decision Making” C. Baunez ABIM 2020, Champéry, Switzerland January 12-16 2020

65-“STN and social cognition ” C. Baunez, EWCBR2020, Villars-sur-Ollon, Switzerland, March 7-14 2020

66-“Are Antifragile Exposures Natural? ” Mickael Degoulet, Louis-Matis Willem, Christelle Baunez*, Stéphane Luchini, Patrick A. Pintus, EWCBR2020, Villars-sur-Ollon, Switzerland, March 7-14 2020

.....STOP COVID.......

Invited seminars (last 5 years)

2015

- Experimental psychology department, University of Sussex, Brighton, UK (Profs. A. Badiani & D. Duka) « The subthalamic nucleus keeps you high on emotion and motivation for drugs of abuse: towards a treatment for addiction? », 22 january 2015

2016

- RosalindFranklin University North Chicago, USA (Prof K. Tseng) « Subthalamic nucleus as the appropriate target for deep brain stimulation treatment of addiction »18 novembre 2016

2017

- Institut de Biologie Paris Seine (IBPS), Université Pierre et Marie Curie, Paris (F. Tronche) « Inactivation of the subthalamic nucleus as a strategy for a treatment of drug addiction » 13 février 2017

2018

- Shanghai Key laboratory of Psychotic disorders, Shanghai Mental Health Center, Shanghai, China (T. Yuan) « The subthalamic nucleus and reward-related processes : towards DBS strategy for drug addiction » 26 Février 2018

- Institute of Neurosciences Shanghai (ION), Shanghai, China (C-C Zhang) « Subthalamic nucleus and DBS treatment for addiction » 27 février 2018

26- McLean Hospital, Boston, USA (invited by S.N. Haber), "Deep brain stimulation of the subthalamic nucleus to treat addiction: frequency matters", 20 août 2018

2019 27-NIDA, Baltimore, USA (invited by C.W. Bradberry) "Deep brain stimulation of the subthalamic nucleus to treat addiction: frequency matters", 11 avril 2019

28-Univ. Minnesota, Minneapolis, USA (invited by S. Heilbronner) "Deep brain stimulation of the subthalamic nucleus to treat addiction: frequency matters", 12 avril 2019

Publications

1 -Baunez C., Nieoullon A. and Amalric M. (1994) NMDA receptor blockade impairs behavioural performance of rats in a reaction-time task: new evidence for glutamatergic-dopaminergic interactions in the striatum, Neuroscience, 61: 521-531

2 -Amalric M., Ouagazzal A., Baunez C. and Nieoullon A. (1994) Functional interactions between glutamate and dopamine in the rat striatum, Neurochem. Int., 25: 123-131

3 -Baunez C., Nieoullon A. and Amalric M. (1995) Dopamine and complex sensorimotor integration: further studies in a conditioned motor task in the rat, Neuroscience, 65: 375-384

4 -Baunez C., Nieoullon A. and Amalric M. (1995) In a rat model of parkinsonism, lesioning the subthalamic nucleus does not simply alleviate the behavioral effects of striatal dopamine depletion, J. Neurosci. 15: 6531-6541

5 -Amalric M., Baunez C. and Nieoullon A. (1995) Does the blockade of excitatory amino acid transmission in the basal ganglia simply reverse reaction time deficits induced by dopamine inactivation?, Behav. Pharmacol. 6: 508-519

6 -Baunez C. and Amalric M. (1996) Evidence for functional differences between entopeduncular nucleus and substantia nigra : effects of APV (DL-2-amino-5- phosphonovaleric acid) microinfusion on reaction time performance in the rat. Eur. J. Neurosci., 8 (9): 1972-1982

7 -Baunez C. and Robbins T.W. (1997) Bilateral lesions of the subthalamic nucleus induce multiple deficits in attentional performance in rats. Eur. J. Neurosci., 9: 2086-2099

8 -Baunez C., Salin P., Nieoullon A. and Amalric M. (1998) Impaired performance in a conditioned reaction time task after thermocoagulatory lesions of the fronto-parietal cortex in rats. Cereb. Cortex 8: 301-309

9 -Baunez C. and Robbins T.W. (1999) Effects of transient inactivation of the subthalamic nucleus by local muscimol and APV infusions on performance on the five-choice serial reaction time task in rats. Psychopharmacology 141: 57-65

10 -Baunez C. and Robbins T.W. (1999) Effects of dopamine depletion of the dorsal striatum and further interaction with subthalamic nucleus lesions in an attentional task in the rat. Neuroscience 92: 1343-1356

11 -Rogers RD, Baunez C, Everitt BJ and Robbins TW (2001) Lesions of the medial and lateral striatum in the rat produce dissociable deficits in attentional performance. Behav. Neurosci. 115(4): 799-811

12 -Baunez C., Humby T., Eagle D, Ryan L. J., Dunnett S.B. and Robbins T.W. (2001) Effects of STN lesions on simple vs choice reaction time tasks in the rat: preserved motor readiness, but impaired response selection. Eur. J. Neurosci. 13(8): 1609-1616.

13 -Centonze D., Picconi B., Baunez C., Borrelli E., Pisani A., Bernardi G. and Calabresi P. (2002) Cocaine and amphetamine depress striatal GABAergic synaptic transmission through D2 dopamine receptors. Neuropsychopharmacology 26(2): 164-175

14 -Baunez C, Amalric M and Robbins TW (2002) Enhanced food-related motivation after bilateral lesions of the subthalamic nucleus. J. Neurosci. 22(2): 562-568

15 - Breysse N, Baunez C, Spooren W, Gasparini F and Amalric M (2002) Chronic but not acute treatment with a metabotropic glutamate 5 receptor antagonist reverses the akinetic deficits in a rat model of parkinsonism. J. Neurosci. 22(13): 5669-5678

16 -Chudasama Y., Baunez C. and Robbins T.W. (2003) Functional disconnection of the medial prefrontal cortex and subthalamic nucleus in attentional performance: Evidence for cortico-subthalamic interaction. J. Neurosci. 23(13): 5477-5485

17 -Darbaky Y., Forni C., Amalric M. and Baunez C. (2003) High Frequency stimulation of the subthalamic nucleus has beneficial antiparkinsonian effects on motor functions in rats, but less efficiency in a choice-reaction time task. Eur. J. Neurosci. 18: 951-956

18 -Bacci JJ, Absi H, Manrique C, Baunez C, Salin P, Kerkerian-LeGoff L (2004) Differential effects of prolonged high frequency stimulation and of excitotoxic lesion of the subthalamic nucleus on dopamine denervation-induced cellular defects in the rat striatum and globus pallidus. Eur. J. Neurosci. 20(12): 3331-3341

19 -Baunez C, Dias C, Cador M, Amalric M (2005) The subthalamic nucleus exerts an opposite control on cocaine and natural rewards. Nature Neuroscience 8(4):484-9 Faculty of 1000 Biology: evaluations for Baunez C et al Nat Neurosci 2005 Apr 8 (4) :484-9 http://www.f1000biology.com/article...

20 -Turle-Lorenzo N, Breysse N, Baunez C, Amalric M (2005) Alleviation of akinesia after chronic metabotropic glutamate receptor 5 blockade is not potentiated by the NMDA antagonist MK801 in 6-OHDA treated rats. Psychopharmacology 179: 117-127

21 -Witjas T, Baunez C, Henry J M, Delfini M, Regis J, Ali Cherif A, Peragut J C, Azulay J P (2005) Addiction in Parkinson’s Disease: Impact of Subthalamic Nucleus Deep Brain Stimulation. Mov. Disord. 20(8): 1052-1055

22 -Centonze D, Gubellini P, Rossi S, Picconi B, Pisani A, Bernardi G, Calabresi P, Baunez C. (2005) STN Lesion Reverses Motor Abnormalities and Striatal Glutamatergic Overactivity in Experimental Parkinsonism. Neuroscience 133: 831-840

23 -Winstanley CA, Baunez C, Theobald DEH, Robbins TW (2005) Lesions to the subthalamic nucleus decrease impulsive choice but impair autoshaping in rats: importance of the basal ganglia in Pavlovian conditioning and impulse control Eur. J. Neurosci. 21: 3107-3116

24 -Darbaky Y, Baunez C, Arecchi P, Legallet E, Apicella P. (2005) Reward-related neuronal activity in the subthalamic nucleus of the monkey. Neuroreport 16(11): 1241-1244

25 -Centonze D, Rossi S, Gubellini P, De Chiara V, Tscherter A, Prosperetti C, Picconi B, Bernardi G, Calabresi P., Baunez C (2006) Deficits of Glutamate Transmission in the Striatum of experimental hemiballism. Neuroscience 143: 213-21

26 -Turle-Lorenzo N, Maurin B, Puma C, Chezaubernard C, Morain P, Baunez C, Nieoullon A, Amalric M (2006) The dopamine agonist piribedil with L-Dopa improves attentional dysfunction: relevance for Parkinson’s disease. J Pharmacol Exp Ther. 319: 914-23

27 -Baunez C, Christakou A, Chudasama Y, Forni C, Robbins TW (2007) Bilateral high frequency stimulation of the subthalamic nucleus on attentional performance: transient deleterious effects and enhanced motivation in both intact and parkinsonian rats. Eur. J. Neurosci. 25: 1187-1194

28 -Eagle DM, Baunez C, Hutcheson DM, Lehmann O, Shah AP, Robbins TW (2008) Stop-signal reaction time task performance: role of prefrontal cortex and subthalamic nucleus. Cerebral Cortex 18(1):178-188.

29 -Lardeux S and Baunez C (2008) According to alcohol preference, the subthalamic nucleus exerts an opposite control on motivation for alcohol in rats. Neuropsychopharmacology: 33: 634-642

30 -Temel Y, Tan S, Vlamings R, Sesia T, Wei LL, Lardeux S, Visser-Vandewalle V, and Baunez C (2009) Cognitive and limbic effects of deep brain stimulation in preclinical studies Frontiers in Biosciences, 14, 1891-1901, [DOI No:10.2741/3349]

31 -Lardeux S, Pernaud R, Paleressompoulle D, Baunez C (2009) Beyond the reward pathway: coding of the reward salience and error in the rat subthalamic nucleus. J. Neurophysiol. 102(4):2526-37 Faculty of 1000 Biology: evaluations for Lardeux S et al J Neurophysiol 2009 Oct 102 (4) :2526-37 http://www.f1000biology.com/article...

32 -Eagle DM and Baunez C (2010) Is there an inhibitory-response control system in the rat? Evidence from anatomical and pharmacological studies Neuroscience and Biobehavioral Reviews 34(1):50-72. Epub 2009 Jul 15

33 -Gubellini P, Salin P, Kerkerian-LeGoff L, Baunez C (2009) Deep brain stimulation in neurological diseases and experimental models: from molecule to complex behavior. Progress Neurobiol. 89(1):79-123

34 -Voon V, Fernagut PO, Wickens J, Baunez C, Diaz-Rodriguez M, Pavon N, Juncos JL, Obeso JA, Bezard E (2009) Abnormal movements and behaviours in Parkinson’s Disease: Role of dopaminergic mechanisms. Lancet Neurol. Dec;8(12):1140-9

35 -Rouaud T*, Lardeux S*, Panayotis N, Paleressompoulle D, Cador M, Baunez C (2010) Reducing the desire for cocaine with subthalamic nucleus deep brain stimulation. P. Natl. Acad. Sci. USA 107:1196-1200, published online 28 dec. 2009, doi:10.1073/pnas.0908189107

36 -Baunez C and Gubellini P (2010) Effects of GPi and STN inactivation on physiological, motor, cognitive and motivational processes in animal models of Parkinson’s disease. Prog. Brain Res. 183: 235-58

37 -Krack P, Hariz M, Baunez C, Guridi J, Obeso J (2010) Deep brain stimulation: from neurology to psychiatry. Trends Neurosci. 33(10):474-84

38 -Baunez C. (2011) A few examples of the contribution of animal research in rodents for clinical application of Deep Brain Stimulation. Prog. Brain Res 194:105-16

39 -Baunez C and Lardeux S (2011) Frontal cortex-like functions of the subthalamic nucleus. Frontiers in systems neuroscience 5:83, doi 10.3389/fnsys.2011.00083

40 -Baunez C., Yelnik J., Mallet L. (2011) Six questions on the subthalamic nucleus: lessons from animal models and stimulated patients. Neuroscience 198:193-204

41 - Pelloux Y and Baunez C (2013) Deep brain stimulation for addiction : why the subthalamic nucleus should be favored. Curr. Op. Neurobiol. 23: 713-720; http://dx.doi.org/10.1016/j.conb.20...

42 - Lardeux S., Paleressompoulle D., Pernaud R., Cador M., Baunez C. (2013) Different populations of subthalamic neurons encode cocaine and sucrose reward and predict error J. Neurophysiol. 110(7):1497-1510

43 - Juan-Francisco Espinosa-Parrilla, Christelle Baunez, Paul Apicella (2013) Linking reward processing to behavioral output: Motor and motivational integration in the primate subthalamic nucleus. Front. Comput. Neurosci. 7 :175. Doi : 10.3389

44 -Marjan Jahanshahi, Ignacio Obeso, Christelle Baunez, Manuel Alegre, Paul Krack and Jose Obeso (2015) Parkinson’s disease, the Subthalamic Nucleus, Inhibition and Impulsivity. Mov. Disord. 30(2):128-40

45 -Pelloux Y, Meffre J, Giorla E, Baunez C The subthalamic nucleus keeps you high on emotion: behavioral consequences of its inactivation. Frontiers Behav Neurosci 8:414 ; doi: 10.3389/fnbeh.2014.00414

46 - Espinosa-Parrilla J-F, Baunez C, Apicella P (2015) Neuronal substrates for action selection based on reward outcomes in the monkey subthalamic nucleus. Eur. J Neurosci 42 : 1705-1717

47 - Hachem-Delaunay S, Fournier M L, Cohen C, Cador M, Baunez C, Le Moine C (2015) Subthalamic nucleus high frequency stimulation modulates neuronal reactivity to cocaine within the reward circuit. Neurobiol. Dis. 80 : 54-62

48 - Breysse E, Y Pelloux, Baunez C (2015) The good and bad differentially encoded within the subthalamic nucleus in rats, eNeuro, 2(5) e0014-15.2015 1–17 DOI: http://dx.doi.org/10.1523/ENEURO.00...

49 - Zenon A , Duclos Y, Carron R, Witjas T, Baunez C, Régis J, Azulay J-P, Brown P, Eusebio A (2016) The Human Subthalamic Nucleus encodes the subjective value of reward and the cost of effort during decision-making. Brain 139(6):1830-43. doi:10.1093/brain/aww075

50 - Tremblay M, Silveira MM, Kaur S, Hosking JG, Adams WK, Baunez C, Winstanley CA (2017) Chronic D2/3 agonist treatment increases preference for uncertainty in rats and alters striatal dopamine signaling. Eur. J. Neurosci. 45(1):159-166. doi: 10.1111/ejn.13332

51 - Wade CL, Kallupi M, Hernandez DO, Breysse E, de Guglielmo G, Crawford E, Koob GF, Schweitzer P, Baunez C, George O (2017) High-frequency stimulation of the subthalamic nucleus blocks compulsive-like re-escalation of heroin taking in rats Neuropsychopharmacology 42(9) : 1850-1859 ; doi:10.1038/npp.2016.270

52 - Pelloux Y and Baunez C (2017) Targeting the subthalamic nucleus in a preclinical model of alcohol use disorder Psychopharmacology, 234(14) : 2127-2137 ; doi: 10.1007/s00213-017-4618-5

53 - Adams WK, Haar CV, Tremblay M, Cocker PJ, Silveira MM, Kaur S, Baunez C, Winstanley CA (2017) Deep-brain stimulation of the subthalamic nucleus selectively decreases risky choice in risk-preferring rats. eNeuro Aug 7;4(4) ; doi: 10.1523/ENEURO.0094-17

54 - Pelloux Y*, Degoulet M*, Tiran-Cappello A, Cohen C, Lardeux S, George O, Koob GF, Ahmed SH and Baunez C (2018) “Subthalamic nucleus inactivation prevents and reverses escalated cocaine use” Mol Psychiatry, 23 : 2266–2276 (online : Jun 7. doi: 10.1038/s41380-018-0080-y)

55 - Pautrat A, Rolland M, Barthelemy M, Baunez C, Sinniger V, Piallat B, Savasta M, Overton P, David O and Coizet V (2018) Revealing a novel nociceptive network that links the subthalamic nucleus to pain processing. eLife 7:e36607 doi: 10.7554/eLife.36607

56 - Montanari C, Giorla E, Pelloux Y, Baunez C (2020) “Subthalamic nucleus mediates the modulation on cocaine self-administration induced by ultrasonic vocalizations playback in rats” Addict Biol. 25(1):e12710. doi: 10.1111/adb.12710. Epub 2018 Dec 28; bioRxiv: doi: https://doi.org/10.1101/450437

57 - Atkinson-Clement C, Cavazzini E, Zénon A, Witjas T, Fluchère F, Azulay J-P, Baunez C, Eusebio A. (2019) Effects of subthalamic nucleus stimulation and Levodopa on decision making in Parkinson’s disease. Mov Disord. 34(3):377-385. doi: 10.1002/mds.27625

58 - Tremblay M, Barrus MM, Cocker PJ, Baunez C, Winstanley CA. (2019) Increased motor impulsivity in a rat gambling task during chronic ropinirole treatment: potentiation by win-paired audiovisual cues. Psychopharmacology (Berl). 236(6): 1901-1915. doi: 10.1007/s00213-019-5173-z.

59 -Pelloux Y, Giorla E, Montanari C, Baunez C (2019) Social modulation of drug use and drug addiction. Neuropharmacology. 159:107545. doi: 10.1016/j.neuropharm.2019.02.027

60 - Boukezzi S, Baunez C, Rousseau P-F, Warrot D, Silva C, Guyon V, Zendjidjian X, Florian N, Guedj E, Nazarian B, Trousselard M, Chaminade T, Khalfa S (2019) Posttraumatic Stress Disorder is associated with altered reward mechanisms during the anticipation and the outcome of monetary incentive cues. NeuroImage: Clinical 2019 Nov 5;25:102073. doi: 10.1016/j.nicl.2019.102073.

61 - Breysse E, Meffre J., Pelloux Y., Winstanley C. A., Baunez C. Decreased Risk-taking and Loss chasing after Subthalamic Nucleus Lesion in Rats. Eur. J. Neurosci. DOI: 10.1111/ejn.14895

Open Archives: bioRxiv

- Giorla E, Nordmann S, Pelloux Y, Roux P, Rosellini S, Davranche K, Huguet P, Carrieri P*, Baunez C* (2018) Presence and familiarity of a peer as key factors to modulate drug intake: translational evidence from rats to cocaine users. bioRxiv, 10.1101/286518

- Tiran-Cappello A, Pelloux Y, Degoulet M, Brocard C, Baunez C Subthalamic optogenetic manipulations: a glimpse at deep brain stimulation mechanisms. bioRxiv: doi: https://doi.org/10.1101/450767

- Degoulet M, Tiran-Cappello A, Baunez C*, Pelloux Y* Reversing compulsive cocaine seeking with low frequency deep brain stimulation of the subthalamic nucleus. bioRxiv doi: https://doi.org/10.1101/451203

Book chapters

- Baunez C., Robbins T.W. and Amalric M. (2002) Inactivating the subthalamic nucleus in the rat induces various cognitive deficits and motivational exacerbation. Dans: Basal Ganglia VII Faull R. and Nicholson L., eds. Plenum Press NYC (USA) pp. 591-602

- Haber .S. N., Deniau J.M., Groenewegen H.J., O’Donnell P., McGinty J.F. and Baunez C., (2005) The ventral/dorsal divide: to integrate or separate. In: Basal Ganglia VIII J.P. Bolam, C.A. Ingham and P.J. Magill (eds), Plenum Press NYC (USA) pp. 437-456

- Baunez C (2009) Surgical strategies for PD based on animal model data: GPi and STN inactivation in intact animals, or PD models, on various aspects of behaviour (motor, cognitive and motivational processes) In: Cortico-subcortical dynamics in Parkinson’s disease Kuei Y. Tseng (Editor), Humana Press & Springer Editorials, pp. 371-391

- Baunez C and Gubellini P (2010) Effects of GPi and STN inactivation on physiological, motor, cognitive and motivational processes in animal models of Parkinson’s disease. Prog. Brain Res. Vol. 183, pages 235-58 Recent Advances in Parkinson’s Disease Ed. A. Björklund and M.A. Cenci `
- Baunez C (2011) Il paraît que certaines maladies sont traitées par des stimulations dans les profondeurs du cerveau. De quoi s’agit-il ? In : « Toutes les questions que vous vous posez sur votre cerveau » (Dir : Alario F-X), O. Jacob (Ed, ISBN 978-2-7381-2569-9).

- Baunez C (2016) Ablative Neurotherapeutics and deep brain stimulation in animal models of psychiatric disorders in Psychiatric Neurotherapeutics: Contemporary Surgical & Device-Based Treatments in Psychiatry, edited by Drs. Rosenbaum, Rauch, Dougherty, & Camprodon, Springer, NY, pp. 187-207

- Baunez C (2016) The subthalamic nucleus and reward-related processes. In: The Basal Ganglia: Novel Perspectives on Motor and Cognitive Functions Ed. JJ Soghomonian, Springer, NY, pp. 319-337

Baunez C and Pelloux Y (2018) Harnessing Circuits for the Treatment of Addictive Disorders . In: Neural Mechanisms of Addiction. Ed. M. Terragrossa, Elsevier

Other publications in french

- Lardeux S., Amalric M. et Baunez C. (2005) Effets de la lésion du noyau subthalamique sur la motivation pour l’alcool chez le rat. Cahiers de l’I.R.E.B. 17: 161-166

- Pelloux Y. et Baunez C. (2013) Effets de la lésion du noyau subthalamique sur la perte de contrôle de la consommation d’alcool chez le rat. Cahiers de l’IREB 21 :69-73

- Pelloux Y. et Baunez C. (2015). La chirurgie au secours des addicts Médecine Science 31 (6-7) :674-679

- Baunez C et Degoulet M (2017) Les nouvelles stratégies thérapeutiques pour les addictions. Lettre de la société des neurosciences

Portfolio

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Publications



  • Adams W.K., Vonder Haar C., Tremblay M., Cocker P.J., Silveira M.M., Kaur S., Baunez C., and Winstanley C.A. (2017). Deep-Brain Stimulation of the Subthalamic Nucleus Selectively Decreases Risky Choice in Risk-Preferring Rats. eneuro, 4: ENEURO.0094-17.2017.


  • Atkinson‐Clement C., Cavazzini É., Zénon A., Witjas T., Fluchère F., Azulay J.‐P., Baunez C., and Eusebio A. (2019). Effects of subthalamic nucleus stimulation and levodopa on decision‐making in Parkinson's disease. Movement Disorders, 34: 377-385.

  • Espinosa-Parrilla J.-F., Baunez C., and Apicella P. (2013). Linking reward processing to behavioral output: motor and motivational integration in the primate subthalamic nucleus. Frontiers in Computational Neuroscience, 7.


  • Espinosa-Parrilla J.-F., Baunez C., and Apicella P. (2015). Modulation of neuronal activity by reward identity in the monkey subthalamic nucleus. European Journal of Neuroscience, 42: 1705-1717.

  • Giorla E., Nordmann S., Pelloux Y., Roux P., Rosellini S., Davranche K., Montanari C., Vilotitch A., Huguet P., Carrieri P., and Baunez C. (2018). Peer presence and familiarity as key factors to reduce cocaine intake: evidence from translational research. .

  • Hachem-Delaunay S., Fournier M.-L., Cohen C., Bonneau N., Cador M., Baunez C., and Le Moine C. (2015). Subthalamic nucleus high-frequency stimulation modulates neuronal reactivity to cocaine within the reward circuit. Neurobiology of Disease, 80: 54-62.


  • Jahanshahi M., Obeso I., Baunez C., Alegre M., and Krack P. (2015). Parkinson's Disease, the Subthalamic Nucleus, Inhibition, and Impulsivity: PD, The STN, Inhibition, and Impulsivity. Movement Disorders, 30: 128-140.


  • Montanari C., Giorla E., Pelloux Y., and Baunez C. (2018). Subthalamic nucleus mediates the modulation on cocaine self-administration induced by ultrasonic vocalization playback in rats. Addiction Biology.


  • Pautrat A., Rolland M., Barthelemy M., Baunez C., Sinniger V., Piallat B., Savasta M., Overton P.G., David O., and Coizet V. (2018). Revealing a novel nociceptive network that links the subthalamic nucleus to pain processing. eLife, 7.


  • Pelloux Y. and Baunez C. (2017). Targeting the subthalamic nucleus in a preclinical model of alcohol use disorder. Psychopharmacology, 234: 2127-2137.


  • Pelloux Y. and Baunez C. (2015). La chirurgie au secours des addictions. Médecine/Sciences, 31: 674-679.

  • Pelloux Y. and Baunez C. (2013). Deep brain stimulation for addiction: why the subthalamic nucleus should be favored. Current Opinion in Neurobiology, 23: 713-720.


  • Pelloux Y., Degoulet M., Tiran-Cappello A., Cohen C., Lardeux S., George O., Koob G.F., Ahmed S.H., and Baunez C. (2018). Subthalamic nucleus high frequency stimulation prevents and reverses escalated cocaine use. Molecular Psychiatry, 23: 2266-2276.


  • Pelloux Y., Giorla E., Montanari C., and Baunez C. (2019). Social modulation of drug use and drug addiction. Neuropharmacology, 159: 107545.


  • Tremblay M., Barrus M.M., Cocker P.J., Baunez C., and Winstanley C.A. (2019). Increased motor impulsivity in a rat gambling task during chronic ropinirole treatment: potentiation by win-paired audiovisual cues. Psychopharmacology, 236: 1901-1915.


  • Tremblay M., Silveira M.M., Kaur S., Hosking J.G., Adams W.K., Baunez C., and Winstanley C.A. (2017). Chronic D 2/3 agonist ropinirole treatment increases preference for uncertainty in rats regardless of baseline choice patterns. European Journal of Neuroscience, 45: 159-166.


  • Wade C.L., Kallupi M., Hernandez D.O., Breysse E., de Guglielmo G., Crawford E., Koob G.F., Schweitzer P., Baunez C., and George O. (2017). High-Frequency Stimulation of the Subthalamic Nucleus Blocks Compulsive-Like Re-Escalation of Heroin Taking in Rats. Neuropsychopharmacology, 42: 1850-1859.


  • Witjas T., Baunez C., Henry J.M., Delfini M., Regis J., Cherif A.A., Peragut J.C., and Azulay J.P. (2005). Addiction in Parkinson's disease: Impact of subthalamic nucleus deep brain stimulation. Movement Disorders, 20: 1052-1055.


  • Zénon A., Duclos Y., Carron R., Witjas T., Baunez C., Régis J., Azulay J.-P., Brown P., and Eusebio A. (2016). The human subthalamic nucleus encodes the subjective value of reward and the cost of effort during decision-making. Brain, 139: 1830-1843.
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