Séminaire de Cédric Bardy sur les IPS chez les patients parkinsoniens

21 octobre 2014

Séminaire de l’équipe P3M à 11h, salle R+4

Modeling neurological disorders in vitro : From single human neurons to clinical symptoms of Parkinson patients

Human cell reprogramming technologies offer access to live human neurons derived from patients and provide a new alternative to model neurological disorders in vitro. Making current models more physiological and realistic is likely to increase translational success. Electro-chemical activity is the essence of nervous system functions in vivo. In this lecture, I will present some recent development we made to improve neuronal activity in culture. I will also present some recent results using these new technologies combined with electrophysiology and single cell next generation sequencing to learn from neurons of Parkinson patients.

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