Peggy Series

28 octobre 2019

ATTENTION c’est UN LUNDI à 11h !

School of Informatics, University of Edinburgh, Scottland, UK

Are Schizophrenia and Autism Disorders of Prediction ?

invitée par Frédéric Chavane

Are Schizophrenia and Autism Disorders of Prediction ? Abstract : A growing idea in computational neuroscience is that perception and cognition can be successfully described in terms of predictive processing or Bayesian inference : the nervous system would maintain and update internal probabilistic models that serve to interpret the world and guide our actions. This approach is increasingly recognised to also be of interest to Psychiatry. Mental illness could correspond to the brain trying to interpret the world through distorted internal models, or incorrectly combining such internal models with sensory information. I will describe work pursued in my lab that aims at uncovering such internal models, using behavioural experiments and computational methods. In health, we are particularly interested in clarifying how prior beliefs affect perception and decision-making, how long they take to build up or be unlearned, how complex they can be, and how they can inform us on the type of computations and learning that the brain performs. In mental illness, we are interested in understanding whether/how the machinery of probabilistic inference could be impaired, and/or relies on the use of distorted priors. I will introduce the emerging field of Computational Psychiatry and describe recent results relevant to the study of Schizophrenia and Autism.

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