LIABEUF Sylvie

Nom : LIABEUF
Prénom : Sylvie
Téléphone : 04 91 32 40 41
Fonction : Ingénieur en techniques biologiques
Grade : IE2
Bureau : 2.23

Présentation

Formation

• Doctorat de Neurosciences (Université de la Méditerranée- Aix Marseille II) 2011

• Maîtrise de Biologie Cellulaire (Université d’Aix-Marseille II - Luminy) 1991

Parcours Professionnel

2017 IE1 - Institut de Neurosciences de la Timone (INT CNRS)-Equipe P3M-Frédéric Brocard

2012 IE2 - Institut de Neurosciences de la Timone (INT CNRS)-Equipe P3M-Laurent Vinay

2005 IE2 - Plasticité et Physiopathologie de la Motricité (P3M CNRS)-Laurent Vinay

2000 Société Natural Implant (Ingénierie Tissulaire)

1996 Laboratoire CNRS Architecture et Fonction des Macromolécules Biologiques (AFMB)

Publications

• Sánchez-Brualla I, Boulenguez P, Brocard C, Liabeuf S, Viallat-Lieutaud A, Navarro X, Udina E, Brocard F. Activation of 5-HT2A receptors restores KCC2 function and reduces neuropathic pain after spinal cord injury. Neuroscience. 2017 Aug 23. pii : S0306-4522(17)30599-7. doi : 10.1016/j.neuroscience.2017.08.033.

Liabeuf S, Stuhl-Gourmand L, Gackière F, Mancuso R, Sanchez-Brualla I, Marino P, Brocard F, Vinay L. (2017) Prochlorperazine Increases KCC2 Function and Reduces Spasticity after Spinal Cord Injury. J Neurotrauma. 2017 Sept 19. doi : 10.1089/neu.2017.5152.

• Brocard C., Plantier V, Boulenguez P., Liabeuf S., Bouhadfane M., Viallat-Lieutaud A., Vinay L. & Brocard F. (2016) Calpain-mediated proteolytic cleavage of sodium channels after spinal cord injury increases the persistent current and contributes to spasticity. Nature Medicine. 2016 Apr ;22(4):404-11

• Bos R, Sadlaoud K, Boulenguez P, Buttigieg D, Liabeuf S, Brocard C, Haase G, Bras H, Vinay L (2013) Activation of 5-HT2A receptors to serotonin upregulates KCC2 function. Proc. Natl. Acad. Sci. USA, 110 : 348-353.

• Viemari J.C., Bos R., Boulenguez P., Brocard C., Brocard F., Bras H., Coulon P., Liabeuf S., Pearlstein E., Sadlaoud K., Stil A., Tazerart S., Vinay L. (2011) Importance of chloride homeostasis in the operation of rhythmic motornetworks. Progress in Brain Research, 2011 ;188:3-14. Review.

• Stil A., Jean-Xavier C., Liabeuf S., Brocard C., Delpire E., Vinay L., Viemari JC. (2011) Contribution of the potassium-chloride co-transporter KCC2 to the modulation of lumbar spinal networks in mice. Eur J Neurosci. 2011 Apr ;33(7):1212-22.

• Boulenguez P., Liabeuf S, Vinay L. (2011) Reduced neuronal inhibition and spasticity following spinal cord injury. Médecine/Sciences 2011 Jan ;27(1):7-9.

• Boulenguez P.*, Liabeuf S.*, Bos R., Bras H., Jean-Xavier C., Brocard C., Stil A., Darbon P., Cattaert D., Delpire E., Marsala M., Vinay L. (2010) Down-regulation of the cation-chloride cotransporter KCC2 contributes to spasticity after spinal cord injury. Nature Medicine. 2010 Mar ; 16(3) : 302-7. * : Co-1er auteur.

• Stil A. ; Liabeuf S. ; Jean-Xavier C. ; Brocard C. ; Viemari J.C. ; Vinay L. (2009) Developmental up-regulation of the potassium-chloride cotransporter type 2 in the rat lumbar spinal cord. Neuroscience 164, 809-821).

• J. Amendola, J.P. Gueritaud, B. Lamotte D’Incamps , C. Bories, S. Liabeuf, C. Allene, A. Pambo-Pambo, J. Durand (2007) Posnatal electrical and morphological abnormalities in lumbar motoneurones from transgenic mouse model of Amyotrophic Lateral Sclerosis. Archives Italiennes de Biologie, 145 : 311-323.

• C. Jean-Xavier, J-F. Pflieger, S. Liabeuf, L. Vinay (2006) Inhibitory Postsynaptic Potentials in Lumbar Motoneurons Remain Depolarizing After Neonatal spinal cord transection. J Neurophysiol 96:2274-2281,

• A Primot, B Baratte, M Gompel, A Borgne, S Liabeuf., JL Romette, F Costantini, L Meijer (2000) Purification of GSK-3 by affinity chromatography on immobilized axin Protein expression and purification 20,394-404

• L Argiro, C Doerig, S Liabeuf, A Bourgois, JL Romette (2000) Production of Sm37-GAPDH a major therapeutical target in human schistosomiasis Biotechnol-Bioeng 68,2 ,136-141

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