David Robbe

14 février 2014

INMED, Team Neuronal dynamics and function of the basal ganglia, Marseille

Action monitoring by the striatum is critical for accurate expression of procedural memories

Invité par Andrea Brovelli

Abstract : In many of our everyday actions we perform specific sequences of movements with kinematic parameters (e.g., movement time, speed, trajectory) precisely adjusted to task-specific constraints⁠. Examples can be seen in the actions involved in driving a car, playing sports, using tools and performing arts. Several weeks to several months of training are necessary for the acquisition of these motor behaviors who are generally referred to as procedural memories⁠. There are converging evidence from lesion and physiological studies using motor sequence tasks in rodents⁠, monkey and human that the sensorimotor region of the striatum contributes to the expression (i.e., execution) of procedural memories. Nevertheless, the exact nature of this contribution remains unclear⁠ and debated⁠, possibly because action execution is the readout of higher order processes such as motor planning or action selection.

In my presentation I will present recent neuronal and behavioral data in rats that reveal a moment-to-moment action monitoring function of the dorsolateral striatum, operating through contextual and movement-reated representations and instrumental for accurate performances of acquired motor procedures. I will argue that this function accounts for a wide range of experimental data and provide a unifying framework to understand the controversial contribution of the basal ganglia to motor control.

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